Preclinical Drug Testing Flashcards

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What is preclinical drug testing?

Preclinical drug testing is testing a new drug in the lab and on animals before it is tried on humans.

To check that the drug is likely to be safe and that it works before testing it on people.

They are first tested on cells, tissues or organs grown in the lab.

Because it is safer and can show harmful effects without risking a person’s health.

Small animals, such as mice or rats, are often used next.

They aim to find out its toxicity and the best dose that makes it work.

Toxicity means how poisonous or harmful a substance is to living cells or organisms.

It is the smallest dose that gives the wanted effect with as few side effects as possible.

To reduce the risk of serious harm and to watch for side effects carefully.

To protect animals, limit their suffering and make sure they are only used when necessary.